Go into your applications folder and open iSync. Just to be sure, click on iSync > About iSync. The latest version of the
iSync Palm Conduit for Panther is 1.2.
Try checking the box for "Force Slow Synchronization".
I had some quirky things happen the first time or two I was syncing -- using iSync and Missing. I had duplicates and all kinds of bizarro stuff. It eventually worked itself out after a few HotSync operations. I would try deleting any duplicates or mistakes on your mac before the sync.
In Missing Sync, check the box next to Mark/Space Memo Pad. I would disable everything but the iSync conduit and Mark/Space MemoPad until you get it running smooth.
Take comfort in knowing your not alone. I did a pretty good job of
trashing my Address Book, but I'm happy to report it's been smooth sailing ever since.
Oh, also...make sure you're running the latest and greatest version of Missing Sync. You can check from updates withing Missing Sync. Just select Missing Sync > Check for updates.
Good luck. Let me know how you make out.
-Chris